Cowboys favored in high-stakes NFC East clash against Eagles

The Dallas Cowboys are the 4.5-point favorite against the Philadelphia Eagles in a Monday night matchup that could determine the direction of both teams' seasons.

The game kicks off at 8:15 p.m. ET on Monday at Lincoln Financial Field. Dallas arrives with a 2-4 record after losing 23-13 to the Green Bay Packers. The Cowboys are 1-2 on the road this season. Philadelphia enters the contest with a 2-4 record following a 25-14 loss to the Carolina Panthers in Week 6. The Eagles are 1-2 at home and have lost four straight games.

Injury reports show both teams playing with missing pieces. Philadelphia will start backup quarterback Tanner McKee because starter Jalen Hurts is out with blood clots. Wide receiver DeVonta Smith is also out due to a hamstring injury. Running back Saquon Barkley is listed as questionable with a hamstring issue but is expected to play. McKee completed 26 of 45 passes for 215 yards and one touchdown in the loss to the Panthers.

Dallas quarterback Dak Prescott completed 34 of 54 passes for 258 yards and one touchdown with two interceptions in the loss to Green Bay. A third interception was nullified by penalty. The Cowboys have been held to 16 points and 13 points in their last two games.

The total points line is set at 43.5. SportsLine's model, which simulates games 10,000 times, projects the under to hit. The under has covered in four of the last five meetings between these two teams. It also hit in each of the last two Dallas games and three of the past four Philadelphia games.

The Eagles are averaging 17.7 points per game this season, which is tied for 28th in the league. Dallas leads the all-time series 75-59, but Philadelphia has won three of the last four matchups. The model is on a 58-48 record for top-rated picks since 2024.